Characterization of Fragile X mental retardation antibodies for use in cross-species immunoblotting, immunohistochemistry, and electron microscopy
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چکیده
Purpose of the document This information is provided on Cogprints for colleagues in the Fragile X field who have requested it directly in the past. It is also a companion work to the article " Human Fragile X gene locus P1 artificial chromosome transgenic mice " from our group (manuscript to be made available on Cogprints). References The information presented here is summarized from the following sources: 1) Analysis of FMR1 PAC transgenic and fmr1 tm1cgr knockout mice 3) The fmr1 tm1cgr knockout mouse is not a molecular null: implications for phenotype
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گزارش یک مورد سندرم ایکس شکننده همراه با ناهنجاری انگشتان
Fragile X Syndrome, the most common cause of inherited mental retardation, results from mutation in fragile X mental retardation gene (FMR1) on long arm of X chromosome, Xq27.3. Clinical features include moderate to severe mental retardation without neurologic deficit, long face, large ears, prominent jaw, macro-orchidism, attention deficit, behavior di...
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تاریخ انتشار 2009